AffiNANOTECH® Aminooxy-PEG2-azide

Availables Sizes: 25 mg, 50 mg, 100 mg, 250 mg, 500 mg, 1 g.

Overview

Aminooxy-PEG2-azide is a PEG-basedPROTAClinkerthat can be used in the synthesis ofPROTACs. Aminooxy-PEG2-azide is also a non-cleavable 2 unit PEGADC linkerused in the synthesis ofantibody-drug conjugates (ADCs) . Aminooxy-PEG2-azide is aclick chemistryreagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.