AffiNANOTECH® Azido-PEG5-alcohol

Availables Sizes: 250 mg, 1 g, 5 g, 10 g, 50 g.

Overview

Azido-PEG5-alcohol is a non-cleavable 5 unit PEGADC linkerused in the synthesis ofantibody-drug conjugates (ADCs) . Azido-PEG5-alcohol is also a PEG-basedPROTAClinkerthat can be used in the synthesis ofPROTACs. Azido-PEG5-alcohol is aclick chemistryreagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.