AffiNANOTECH® Azide-PEG3-Tos

Availables Sizes: 100 mg, 250 mg, 500 mg, 1 g.

Overview

Azide-PEG3-Tos is a PEG-basedPROTAClinkerthat can be used in the synthesis ofPROTACs. Azide-PEG3-Tos is also a non-cleavable 3 unit PEGADC linkerused in the synthesis ofantibody-drug conjugates (ADCs) . Azide-PEG3-Tos is aclick chemistryreagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.