AffiNANOTECH® Azido-PEG4-Val-Cit-PAB-OH

Availables Sizes: 25 mg, 50 mg, 100 mg, 200 mg, 500 mg.

Overview

Azido-PEG4-Val-Cit-PAB-OH is a cleavable 4 unit PEGADC linkerused in the synthesis ofantibody-drug conjugates (ADCs) . Azido-PEG4-Val-Cit-PAB-OH is also a PEG-basedPROTAClinkerthat can be used in the synthesis ofPROTACs. Azido-PEG4-Val-Cit-PAB-OH is aclick chemistryreagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.