AffiNANOTECH® Azido-PEG3-Val-Cit-PAB-PNP

Availables Sizes: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg.

Overview

Azido-PEG3-Val-Cit-PAB-PNP is a cleavable 3 unit PEGADC linkerused in the synthesis ofantibody-drug conjugates (ADCs) . Azido-PEG3-Val-Cit-PAB-PNP is also a PEG-basedPROTAClinkerthat can be used in the synthesis ofPROTACs. Azido-PEG3-Val-Cit-PAB-PNP is aclick chemistryreagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.