AffiNANOTECH® Azide-PEG4-VC-PAB-Doxorubicin

Availables Sizes: 10 mM * 1 mL in DMSOready for reconstitution, 10 mM * 1 mL in DMSO, 1 mg, 5 mg, 10 mg, 50 mg, 100 mg.

Overview

Azide-PEG4-VC-PAB-Doxorubicin is a agent-linker conjugate composed of a cytotoxic anthracyclineantibioticDoxorubicin and a linker Azide-PEG4-VC-PAB to make antibody agent conjugate (ADC) . Azide-PEG4-VC-PAB-Doxorubicin is aclick chemistryreagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.