AffiNANOTECH® Glucocorticoid receptor modulator 3

Availables Sizes: 50 mg, 100 mg, 250 mg.

Overview

Glucocorticoid receptor modulator3 (Payload 6) is a thioester-containingglucocorticoid receptormodulator (IC50=0.6 nM) .Glucocorticoid receptor modulator3 is designed to inactivate unconjugated payloads rapidly through liver metabolism, thereby minimizing systemic exposure.Glucocorticoid receptor modulator3 can be utilized in the development ofantibody-drug conjugates (ADCs) targeting autoimmune diseases.