AffiNANOTECH® TCO-PEG4-DBCO

Availables Sizes: 5 mg, 10 mg, 50 mg.

Overview

TCO-PEG4-DBCO is a PEG-basedPROTAClinkercan be used in the synthesis ofPROTACs. TCO-PEG4-DBCO is a cleavableADC linkerused in the synthesis ofantibody-drug conjugates (ADCs) . TCO-PEG4-DBCO is aclick chemistryreagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. TCO-PEG4-DBCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.