AffiNANOTECH® Tubulysin A intermediate-1

Availables Sizes: 50 mg, 100 mg, 250 mg.

Overview

Tubulysin Aintermediate-1 is an intermediate in the synthesis of the cytotoxic peptideTubulysin A (HY-15995) .Tubulysin A (TubA) is anantibiotic, anti-microtubule toxins, andapoptosisinducer isolated from myxobacteria.Tubulysin Ahas anti-angiogenic, anti-microtubule, anti-mitotic, and anti-proliferative activities.Tubulysin Aarrests cells in the G2/M phase, effectively inhibits tubulin polymerization, and induces depolymerization of detached microtubules.Tubulysin Aacts as anADC cytotoxin (ADC Cytotoxin) to synthesize ADC.