AffiNANOTECH® β-Glucuronide-dPBD-PEG5-NH2
CAT# AFG-MCX-0792
Size: 100 mg
Availables Sizes: 50 mg, 100 mg, 250 mg.
Overview
β-Glucuronide-dPBD-PEG5-NH2 is the β-glucuronide-linked pyrrolobenzodiazepine dimer, which binds to the prenylated antibody for synthesis of antibody-drug conjugate (ADC) cIRCR201-dPBD. β-glucuronide-linkage as acleavable linker. β-Glucuronide-dPBD-PEG5-NH2, as a proagent of cIRCR201-dPBD, reduces side effects. β-Glucuronide-dPBD-PEG5-NH2 can induceapoptosisand arrest cell cycle. β-Glucuronide-dPBD-PEG5-NH2 has antitumor activity.
Isotype
N/A.
Species
N/A.
Target
N/A.
Appearance
N/A.
Shipping Conditions
Room Temperature.
Storage Conditions
Store the product under the recommended conditions in the Certificate of Analysis.