AffiNANOTECH® Tesirine
CAT# AFG-MCX-1055
Size: 100 mg
Availables Sizes: 1 mg, 5 mg, 10 mg, 50 mg, 100 mg.
Overview
Tesirine (SG3249) is an antibody-drug conjugate (ADC) pyrrolobenzodiazepine (PBD) dimer payload. Tesirine combines potent antitumor activity with desirable physicochemical properties such as favorable hydrophobicity and improved conjugation characteristics.SG3199 (HY-101161) is the released warhead component of the ADC payload Tesirine.SG3199retains picomolar activity in a panel ofcancercell lines. PBD dimers are highly efficient DNA minor groove cross-linking agents with potent cytotoxicity.
Isotype
N/A.
Species
N/A.
Target
N/A.
Appearance
Solid.
Shipping Conditions
Room Temperature.
Storage Conditions
(-) 20°C, protect from light, stored under nitrogen*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen) .