AffiNANOTECH® N3-C4-NHS ester

Availables Sizes: 100 mg.

Overview

N3-C4-NHS ester is a noncleavableADC linkerused in the synthesis ofantibody-drug conjugates (ADCs) . N3-C4-NHS ester is aclick chemistryreagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.