AffiNANOTECH® DBCO-PEG3-TCO

Availables Sizes: 50 mg, 100 mg, 250 mg.

Overview

DBCO-PEG3-TCO is a non-cleavable 3 unit PEGADC linkerused in the synthesis ofantibody-drug conjugates (ADCs) . DBCO-PEG3-TCO is aclick chemistryreagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG3-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.