AffiNANOTECH® DBCO-PEG4-VC-PAB-MMAE
CAT# AFG-MCX-1221
Size: 100 mg
Availables Sizes: 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg.
Overview
DBCO-PEG4-VC-PAB-MMAE consists aADC linker (DBCO-PEG4-VC-PAB) and a tubulin polymerization inhibitor MMAE (HY-15162) . DBCO-PEG4-VC-PAB-MMAE can be used in the synthesis of antibody-agent conjugates (ADCs) . MMAE is a synthetic derivative of dolastatin 10 and functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. DBCO-PEG4-VC-PAB-MMAE is aclick chemistryreagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Isotype
N/A.
Species
N/A.
Target
N/A.
Appearance
Solid.
Shipping Conditions
Room Temperature.
Storage Conditions
Powder-20°C3 years*The compound is unstable in solutions, freshly prepared is recommended.