AffiNANOTECH® DBCO-NHS ester 3

Availables Sizes: 50 mg, 100 mg, 250 mg.

Overview

DBCO-NHS ester 3 (Compound 12) is acleavable linkerthat is used for making antibody-drug conjugate (ADC) . DBCO-NHS ester 3 is a derivative of Dibenzylcyclooctyne (DBCO) obtained by activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC) . DBCO-NHS ester 3 is aclick chemistryreagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.