AffiNANOTECH® Cofetuzumab pelidotin
CAT# AFG-MCX-1342
Size: 100 mg
Availables Sizes: 1 mg, 5 mg, 10 mg, 50 mg, 100 mg.
Overview
Cofetuzumab pelidotin (PF-06647020) is aPTK7-targetingADCcomprising a humanized anti-PTK7 mAb (hu6M024, IgG1) joined to anauristatinmicrotubule inhibitor payload, auristatin-0101 (Aur0101; HY-12522), by a cleavable valine-citrulline (vc) -based linker. Cofetuzumab pelidotin has a DAR of 4. Cofetuzumab pelidotin binds to cell-surface PTK7 with anEC50of 1153 pM by flow cytometry. Cofetuzumab pelidotin has the potential for solid tumors research.
Isotype
Human IgG1 kappa.
Species
Humanized.
Target
N/A.
Appearance
Liquid.
Shipping Conditions
Dry Ice.
Storage Conditions
Store the product under the recommended conditions in the Certificate of Analysis.