AffiNANOTECH® (S, R, S) -MI-1061
CAT# AFG-MCX-1344
Size: 100 mg
Availables Sizes: 50 mg, 100 mg, 250 mg.
Overview
(S, R, S) -MI-1061 is the isomer ofMI-1061 (HY-125858) . (S, R, S) -MI-1061 can used to synthesizeAntibody-Drug Conjugates (ADCs) .MI-1061is a potent, orally bioavailable, and chemically stableMDM2 (MDM2-p53 interaction) inhibitor (IC50=4.4 nM;Ki=0.16 nM) .MI-1061potently activatesp53and inducesapoptosisin the SJSA-1 xenograft tumor tissue in mice. Anti-tumor activity.
Isotype
N/A.
Species
N/A.
Target
N/A.
Appearance
N/A.
Shipping Conditions
Room Temperature.
Storage Conditions
Store the product under the recommended conditions in the Certificate of Analysis.