AffiNANOTECH® Iptacopan

Availables Sizes: 10 mM * 1 mL in DMSOready for reconstitution, 10 mM * 1 mL in DMSO, 5 mg, 10 mg, 50 mg, 100 mg, 200 mg, 500 mg.

Overview

Iptacopan (LNP023) is a first-in-class, orally bioavailable, highly potent and highly selectivefactor Binhibitor with anIC50value of 10 nM. Iptacopan shows direct, reversible, and high-affinity binding to human factor B with aKDof 7.9 nM. Iptacopan targets the underlying cause of complement 3 glomerulopathy (C3G) .