AffiNANOTECH® Mitazalimab
CAT# AFG-MCX-0001
Size: 100 mg
Availables Sizes: 1 mg, 10 mg, 50 mg, 100 mg.
Overview
Mitazalimab (ADC-1013; JNJ-64457107) is FcγR-dependentCD40agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, e.g. dendritic cells (DC), to initiate tumor-reactive T cells. Therefore, Mitazalimab induces tumor-specific T cells to infiltrate and kill tumors. Mitazalimab remodels the tumor-infiltrating myeloid microenvironment.
Isotype
Human IgG1 lambda1.
Species
Human.
Target
CD40.
Appearance
Liquid.
Shipping Conditions
Dry ice
Storage Conditions
Powder: -20°C 3 years /4°C 2 years
In solvent: -80°C 6 months /-20°C 1 month.